Patients Should Never Take These Medications After Weight Loss Surgeries

Patients Should Never Take These Medications After Weight Loss Surgeries

What are NSAIDS?Non-steroidal anti-inflammatory drugs, or NSAIDs, are a group of medications commonly used to treat pain and conditions like arthritis. They reduce pain, inflammation and reduce fevers. NSAIDs commonly interact with other medications, but Weight Loss Surgeries patients should also avoid using NSAIDs. NSAIDs increase the chances of getting a stomach ulcer, and these are much more difficult to treat in Weight Loss Surgeries patients. Common NSAIDs include asprin, ibuprofen, Advil, Motrin, Aleve, Naprosyn, Vioxx and Celebrex. Most Weight Loss Surgeries patients are prescribed medicines that help prevent ulcers.


1. Aspirin should be avoided after Weight Loss Surgeries– even use of baby aspirin to reduce risk in those with known risk factors or a strong family history of heart disease, must be weighed by your health professionals for risk versus benefit.

2. IBUPROFEN – a wide range of name brand products and include the main compounds IBUPROFEN which is in Advil and Motrin, and NAPROXEN which is the brand name Aleve. We often hear “I can’t remember which one I’m not supposed to take!” The answer is that we should not take Advil, Motrin and Aleve.

3. COX-2 inhibitors are also prescribed for pain and should not be taken after Weight Loss Surgeries. Currently Celebrex is the main brand that people know from this category.

4. Steroids delay healing in the stomach and impair the stomach lining’s ability to form the protective layer between the muscle wall and acid. This can lead to an ulcer, bleeding or perforation. Examples of steroids are prednisone, decadron, depo-medrol, and solu-cortef.Steroids should be avoided the first 6 weeks after surgery and then if required should be accompanied by a proton pump inhibitor (PPI) medication. Steroid injections into a joint or the back don’t usually affect the stomach so don’t require taking PPI’s.So if you must take steroids, you must take also take Prilosec, Prevacid, Aciphex, Protonix, Nexium or Zegarid as protection for as long as 30 days after your steroid treatment has ended. Some antacids that are not acceptable protection include Pepcid, Zantac, and Tagamet.

5. Osteoporosis & treatments – Studies have shown that Weight Loss Surgeries patients have a higher incidence of osteoporosis leading to increased risk of fractures. It is fairly common for a Primary Care physician to see lab results of a bone scan and prescribe a bone building regimen, however ulceration of the small pouch can cause death, therefore it is important to choose the treatment least likely to cause an ulcer. Bariatric surgeons often advise patients not to take these treatment meds unless as a last resort. Examples of these drugs are: Fosamax, Boniva, Reclast, Aclasta, and Actonel.

Studies show that Actonel (risedronate) appears be the safer drug for the treatment of osteoporosis in Weight Loss Surgeries patients. Actonel is available in daily, weekly, or monthly dosing; this flexibility may induce better adherence. If you need this type of treatment, discuss monthly or yearly dose versions, make sure you remain upright for a period after the medication and be aware of any heartburn, indigestion or abdominal pain so you can stop taking it and report to your physician. If financially feasible, intravenous Reclast (zoledronic acid), should be considered.

6. Nicotine from smoking is one of the worst things patients can do after Weight Loss Surgeries, due to the high risk of ulceration of the stomach. Don’t smoke! I know a brilliant and charming businessman who 8 months after Weight Loss Surgeries nearly died when nicotine ate a hole in his pouch and his stomach contents emptied into his abdominal cavity. He woke up in ICU and learned he had been there for six weeks, three of them as a John Doe as he was walking without ID when his medical issue occurred. He had quit smoking for his surgery, but started back. It took two surgeries and six months for him to recover.source

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